Ketoconazole. Cas No: 65277-42-1

Cas No:65277-42-1

Ketoconazole is used in the treatment or prevention of fungal infections including blastomycosis, candidiasis, coccidioidomycosis, histoplasmosis, chromomycosis, and paracoccidioidomycosis

Chemical formula :C26H28Cl2N4O4

Ketoconazole interacts with 14-?-sterol demethylase, a cytochrome P-450 enzyme necessary for the conversion of lanosterol to ergosterol.This results in inhibition of ergosterol synthesis and increased fungal cellular permeability due to reduced amounts of ergosterol present in the fungal cell membrane